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Lipid hydroperoxides, generated primarily through the activity of lipoxygenases (LOXs), are key mediators of cellular dysfunction and death ( 2.1.3 Antioxidant system 2.1.3.1 System Xc-/GSH/GPX4 axis The cystine/glutamate antiporter (System Xc-), glutathione (GSH), and glutathione peroxidase 4 (GPX4) form a critical antioxidant axis that plays a central role in regulating ferroptosis

doi: 10.1007/s11033-020-05602-4 126 HaoJLiuY

Glutathione is often referred to as the "master antioxidant" due to its role in supporting cellular function and oxidative balance

10.1038/s41586-019-1195-2 82 MawuenyegaK

Glutathione should be used while breastfeeding only if the potential benefits justify the potential risks to the child, as determined by your doctor