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Analysis was performed in negative ion mode at a resolution of 140,000 for the full MS scan in a data-dependent mode

Leventhal-Perek, S., Shani, M

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With millions of Americans using GLP-1s, many are wondering how the use of these medications affects another public health concern: osteoporosis

In animals, GLP-1R engagement was demonstrated through glucose-tolerance, food-intake, and gastric-emptying readouts, while GCGR engagement was tracked through liver nicotinamide N-methyltransferase (NNMT) messenger-RNA expression and circulating biomarkers including amino acids and fibroblast growth factor-21 (FGF-21)