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It causes an immediate release of almost all the granules (containing serotonin, histamine, chemokines, cytokines, enzymes, heparin, and prostaglandins), which trigger itching, swelling, mucous, and anaphylaxis.[ref] A delayed response by mast cells comes from the formation of other mediators, such as prostaglandin D2

During the course, glucagon-like peptide-2 (GLP-2) enhanced intestinal epithelial cells proliferation and reduced gut permeability, thereby stabilizing the intestinal mucosal barrier

Statistical tests in RT-qPCR assays were from the dCt values

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Lin MJ, Dai W, Scott MJ et al (2017) Metformin improves nonalcoholic fatty liver disease in obese mice via down-regulation of apolipoprotein A5 as part of the AMPK/LXR signaling pathway