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"Expression and purification of 15 N- and 13 C-isotope labeled 40-residue human Alzheimer's -amyloid peptide for NMR-based structural analysis"

The association of APR-246 and ferroptosis inducers has a synergistic anti-leukemic activity in vitro We next determined whether targeting ferroptosis pathways in combination with APR-246 can increase the antileukemic activity of this compound, mimicking SLC7A11 inhibition

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One significant aspect of this interaction is the microglial response to endothelial dysfunction within the BBB, which acts as a major contributor to inflammation and oxidative stress in the CNS