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the effect remains weak and not significant for doses 2, 4 and 8 times higher respectively

In AD, mitochondrial abnormalities, including impaired electron transport chain function and reduced mitochondrial biogenesis, lead to increased ROS production and diminished ATP generation

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Vitamin C may promote resistance to infection by the activation of leukocytes, production of interferon, and regulation of the inflammatory process

To that end, we applied PAGE both with the conventional (migration direction from anode to cathode) and with the inverted polarity (migration direction from cathode to anode) (Fig