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Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines

Mauras N, OBrien KO, Welch S, Rini A, Helgeson K, Vieira NE, Yergey AL

Their diverse biological effects, coupled with a growing body of preclinical and clinical evidence, support the potential for GLP-1R agonists to be integrated into multidisciplinary pain management protocols

Novo Nordisk expects to receive a decision from the FDA by the end of the year on its approval request for a tablet version of semaglutide