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Chronic inflammation is sustained by a lack of Notch signaling leading to toll-like receptor stimulation with subsequent TNF- and IL-1 secretion causing dendritic cell activation and IL-23 release which polarizes Th17 cells and leads to increased IL-17

I felt like there was no way I could win like my body had stacked the deck against me

Tears in the lining of the anus, often from passing hard stools, cause sharp pain with bowel movements and small amounts of bright red blood

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Dosing: 1000-2000mg combined EPA/DHA daily from quality fish oil or algae supplements