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Protective effect of neuropeptide substance P on bone marrow Mesenchymal stem cells against apoptosis induced by serum deprivation

The reduced ability to conjugate glutathione may increase toxic load and oxidative stress

G6PD deficiency is more common in people of African, Middle Eastern, or Mediterranean descent and provides protection against malaria

The safety profile at doses below those studied in clinical trials is not well characterized, and there is no FDA approval for this indication

More than a dozen trials are now underway globally testing semaglutide, tirzepatide, and oral GLP-1 formulations for alcohol, nicotine, opioid, and stimulant addiction