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Constitutive overexpression of Nrf2-dependent heme oxygenase-1 in A549 cells contributes to resistance to apoptosis induced by epigallocatechin 3-gallate

By increasing the sensitivity of cells to insulin, GLP-1RAs help the body to regulate blood sugar levels more effectively, which can reduce the risk of developing NAFLD [21,22] (Figure 2)

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Along with enhanced ER stress, oxidative stress and neuroinflammation are also inducers to neuronal apoptosis (Redza-Dutordoir and Averill-Bates 2016)