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Anandhan A, Lei S, Levytskyy R, Pappa A, Panayiotidis MI, Cerny RL, et al

This dual action may result in more potent effects on weight loss compared to medications that target either GIP or GLP-1 receptors alone

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For instance, in a randomized, placebo-controlled trial in healthy adults, subcutaneous CJC-1295 injections produced sustained, dose-dependent increases in GH (two to 10 times) and IGF-1 (1.5 to three times) levels over several days, demonstrating prolonged GH axis stimulation without serious adverse effects, a hormonal milieu associated with anabolic and metabolic effects

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