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MDM2 upregulation induces mitophagy deficiency via Mic60 ubiquitination in fetal microglial inflammation and consequently neuronal DNA damage caused by exposure to ZnO-NPs during pregnancy
Even without genetic variations, constant stress, like from toxins or environmental causes, also affects the activity of genes and, therefore, the enzymes
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The percentage of dead cells was presented as % of PI positive cells based on 10,000 events per sample
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