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Overall, SCs appear to induce depression-like effects through overlapping mechanismsincluding monoamine imbalance, oxidative stress, and mitochondrial dysfunctionthat may converge on persistent epigenetic alterations

Other Small Molecular Targets The receptor activation of cannabinoid (CB)-1/2 involves the production of endocannabinoids, subsequently, endocannabinoids are quickly metabolized by specific fatty acid amide hydrolase (FAAH) (176)

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