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It might sound strange at first that a diabetes and weight loss drug has the potential to treat addiction disorders, but observations from researchers have led to emerging data, anecdotal reports, and pharmacoepidemiologic findings that suggest GLP-1 drugs could be effective for addiction by reducing drug use and craving through the modulation of reward pathways, stress responses, and cognitive functions

FDA and the PCAC do review clinical input from practitioners, and well-documented comments describing clinical outcomes, patient need, or safety observations can meaningfully inform the Committees recommendations

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