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It helps restore inhibitory nervous system control when neuro-active insecticideslike isoxazoline (including NexGard, Bravecto, Simparica and Credelio) partially cross into mammalian GABA receptor pathways, reducing inhibitory braking and enabling excitatory overload
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We used a human BBB co-culture model improved by cARLA treatment, as described in our paper [40], for the impedance, cellular uptake and permeability experiments
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