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E-mail: [email protected] Date of Received: 28-12-2010 Date of Accepted: 06-06-2011 Available Online: 15-08-2011 Abstract The primary role of glutathione transferase is to defend an organism from toxicities through catalyzing the reaction of glutathione (GSH) with potentially toxic compounds or metabolites to their chemically and biologically inert conju-gates

5-Fluorouracil enhances the antitumor activity of the glutaminase inhibitor CB-839 against PIK3CA-mutant colorectal cancers

Fatigue reduces exercise, which leads to more muscle loss and weight gain

TZ conceived and coordinated the study