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7).Nuclear factor (erythroid-derived 2)-like 2 factor is the master regulator of antioxidant protein expression in the cell which protects it from oxidative damage triggered by injury and inflammation, whereas inducible nitric oxide synthase (iNOS) is responsible for producing large quantities of NO

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Goldspinks laboratory at the Medical College of Wisconsin has specifically characterised IGF-1 isoform activity in cardiac tissue, demonstrating MGFs role in preventing cardiomyocyte death, preserving contractility, and preventing pathological hypertrophy following myocardial infarction in animal studies

Antioxidants like selenium and beta-carotene support immune cell function by reducing oxidative damage

doi: 10.1038/s41893-018-0046-8 72 Molnr.PappM.KovcsD