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However, there have been no publications reporting objective quantification of CALM pigmentation (11)

The drug is not affected by food intake

doi:10.1002/hlca.19770600434 Graf MV, Roszak AW, Kovalzon VM, et al

Regular thyroid function monitoring should continue, typically at 36 months after starting Wegovy, as weight loss may alter levothyroxine requirements

If patients respond well and experience minimal side effects, the dose can be increased to 50 mg twice daily or adjusted further as clinically appropriate