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Studies based on changes to the LIP level have revealed that iron overload or ferritinophagy induction increases cell sensitivity to ferroptosis [21,22,23,24]

Key Points Aberrant c-MET pathway activation occurs frequently in gastrointestinal tumours and can result from multiple mechanisms, including c-MET protein overexpression, MET amplification or enhanced transcription and/or aberrant autocrine or paracrine secretion of HGF Activated c-MET signalling results in enhanced cancer cell proliferation, survival and invasion

[43] Measurement of static lung volumes using body plethysmography or other techniques typically reveals reduced lung volumes (restriction)

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For extended storage, aliquot into sterile containers and freeze at -20C