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Isolation of INS-1-derived cell lines with robust ATP-sensitive K+channel-dependent and -independent glucose-stimulated insulin secretion

Its activity can be enhanced by altering the phospholipid composition of fat droplets and is complemented by gastric lipase's partial hydrolysis of triglycerides

2BPC157 The BPC157 peptide synthesis process of the pilot scale of embodiment 2 12020g(Loadding1.0mmol/g)1TBTU/HOBt-24gHPLC751C 18 (Kromasil-C 18 30mm*250mm)13.6gHPLC98 Referring to the specific process of Example 1, the difference is that all reagents are directly amplified 20 times, that is, 20 g of Wang's resin (Loadding: 1.0 mmol/g) is weighed for reaction, and the TBTU/HOBt reaction of Example 1 is also used to prepare the resin - Peptide conjugates, cleaved to prepare crude peptides, a total of 24 g of crude products were obtained, with a purity of 75% as determined by HPLC

Guo Y, et al