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Homocysteine can be diverted into the trans-sulfuration pathway, being the precursor of cysteine, which will be used in GSH production together with glycine and glutamate

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While starting prandial insulin therapy, it is advised to continue using metformin, thiazolidinediones (TZDs), dipeptidyl peptidase-4 (DPP-4) inhibitors, and sodium-glucose cotransporter 2 (SGLT2) inhibitors [20]

Li Y, Perry T, Kindy MS, Harvey BK, Tweedie D, Holloway HW et al (2009) GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

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