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Topical formulations (typically 0.1% to 2% concentration creams or serums) are applied directly to target tissue areas such as skin, scars, or joints

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Clinical Use: Frequently incorporated in musculoskeletal injury recovery plans

55 Not only that, but they have also been found to improve the histological characteristics of the liver by promoting the oxidation of fatty acids, 56 steatosis of the liver, 57 significantly reducing liver fat content (LFC), 58 effectively regulating inflammation caused by fat accumulation in the liver

Furthermore, TMAO enhances CaOx crystal deposition via oxidative stress and autophagy-related cell death, impairs renal function, and promotes kidney stones (Figure 9A)