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[6] Children in some regions of developing countries are at particular risk due to increased requirements during growth coupled with diets low in animal-sourced foods

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Unlike direct growth hormone supplementation, it stimulates the pituitary gland to produce its own GH, working with the body's regulatory mechanisms rather than bypassing them

Metformin, commonly prescribed for type 2 diabetes, is well-known to cause diarrhoea and is also associated with B12 deficiencymeaning patients may be taking both simultaneously