A 2026 review in the American Journal of Sports Medicine emphasizes that despite popularity, "significant research regarding the safety and efficacy of these therapeutic methods is required before definitive recommendations can be made to patients." Only a single human case series exists for BPC-157 (for knee pain), with significant methodological flaws and no controls
Effects of Microecological Regulators on Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials
[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Heppner K.M., Kirigiti M., Secher A., Paulsen S.J., Buckingham R., Pyke C., et al
"[I was] eating a whole tub of ice cream every night and then feeling bad about myself, making myself get up early in the morning and go to the gym for an hour and a half and running on that treadmill until sometimes my back would hurt," she shared
One study in the journal Addiction found that people addicted to alcohol who also had a prescription for Ozempic or similar drugs had a 50% lower rate of binging alcohol, compared to those who were not on the medications