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Those with genetic predispositions affecting appetite regulation or glucose metabolism may benefit from baseline biomarker assessment to support informed decision-making with their healthcare team

[1] [10] However, gastrointestinal side effects such as severe vomiting and diarrhea can lead to dehydration and acute kidney injury

It is common, for example, for a patient reporting nausea or digestive discomfort early on to remain at that stage longer before any further increase is considered

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Animal research: preclinical model studies examining pathway-level and metabolic model questions