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It was approved by the U.S

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0.5 mg once weekly for the next 4 weeks if tolerated 1 mg once weekly for the next 4 weeks if tolerated Maximum dose of 2 mg once weekly ongoing if further dose escalation is required Wegovy is titrated over 16-20 weeks

191 This effect was less pronounced in healthy non-obese women with a decrease of insulin release from 108 to 49.3 nmol min/l ( P =0.05)