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doi: 10.1152/ajpcell.00946.2024 43 WangWLiLLiXChenJWangRYangQet al

Extended Data Figure 4 summarizes the global importance of wtIDH1 on biochemical pathways, and in particular ones that impact mitochondrial function and redox homeostasis

In murine macrophages, apigenin treatment (100 M) inhibited NO production, expression of cytokines IL-1, IL-6, COX-2 and iNOS, and MAPK signaling molecules, including ERK and JNK in a noncytotoxic manner [135]

Bottom line: A multi-nutrient approach that combines high-bioavailability glutathione with supporting antioxidants often yields the most visible results for skin tone and clarity

Advanced Biomedical Research