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For the same 220-pound person, 22.5% means losing roughly 50 pounds, nearly 17 more pounds than semaglutide would produce on average

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When people lose weight, some lean mass is often lost too

According to previous reports by GPCR3D, Retatrutide (LY3437943) is a triple agonist peptide developed by Eli Lilly that targets the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R)