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Laboratory investigations show restored kidney function in both fast aging and naturally aged mouse models, suggesting senescent cell elimination can reverse organ-specific age-related decline

Carruthers, 2017) show no cumulative toxicity over a decade of treatment, no measurable atrophy of treated muscle beyond what reverses on discontinuation, and stable result reproducibility across product brands

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and 2) a trial-product estimand which includes data collected from all randomized participants prior to premature trial-product discontinuation or initiation of rescue medication ( SIDEBAR 2 )

They represent real setbacks for real people who worked hard to achieve their results