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Many people do not realize they have it until the disease has already progressed

doi: 10.1210/endo-121-3-1076

Sekhar RV, McKay SV, Patel SG, Guthikonda AP, Reddy VT, Balasubramanyam A, et al

It is based on a simplified model

In the gastrointestinal tract, delayed gastric emptying slows nutrient delivery and contributes to early satiety, while central actions on GLP1 receptorpositive neurons in the hypothalamus and brainstem reduce hunger and alter rewardrelated eating behavior