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The STEP 1 extension study showed approximately two-thirds of weight was regained within one year of stopping semaglutide

Common digestive side effects include: Nausea (affecting up to 44% of patients in clinical trials) Diarrhoea (approximately 30% of patients) Constipation (around 24% of patients) Vomiting (reported by roughly 24% of patients) Abdominal pain, bloating, and dyspepsia Gastro-oesophageal reflux symptoms These effects are typically most pronounced during dose escalation and often improve as the body adapts to the medication

These good effects reach past just weight loss

However, the appetite-suppressing effects of semaglutide GLP-1 are gradual and may not be immediately noticeable after your first injection

Strategies for Managing Nausea and Digestive Discomfort To deal with stomach side effects, try changing your diet and maybe the timing of your medicine