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[14] [15] You should temporarily stop taking metformin during acute illnesses that may cause dehydration (such as severe vomiting, diarrhoea, or fever), before certain procedures, or if you have heavy alcohol intake ('sick-day rules')
no clinical trials validate the combination
What started as a class of medications for type 2 diabetes moved into weight loss, and has since expanded into treating fatty liver disease (also known as metabolic dysfunction-associated steatohepatitis, or MASH), specific cardiovascular diseases, obstructive sleep apnea, and the list continues to grow
Both systems complement the GSH system in determining protein thiol/disulfide status, a primary factor in redox signaling
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