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Furthermore, the bulk of discovered gene areas contain genes relevant to immune pathways, proving that MS is an immunologically mediated illness [5, 6]

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1 Introduction Kidney transplantation, the preferred treatment for stage 4 chronic kidney disease (CKD), achieves 1-year, 5-year, and 10-year survival rates of 91%, 77%, and 56%, respectively ( The pathogenesis of kidney allograft fibrosis is complex, involving both immune-mediated and non-immune factors (6, 7)