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According to manufacturer info, its big advantage is that it's compatible both with other silicones and with natural plant oils, so it's a great ingredient to formulate products with good-sounding, consumer-pleasing vegetable oils but still maintain a cosmetically elegant, non-greasy and non-tacky feel

That substitution is the core mistake that shows up in many of the problems listed below

Thymosin Beta-4 was originally identified as a thymic hormone involved in T-cell differentiation, but its functional significance is now understood to extend well beyond the immune system

PloS One (2016) 11(7):e0158205