For T0901317 experiments, mice were injected intraperitoneally with either vehicle (10%DMSO in 90% corn oil) or T0901317 (MedChem Express, HY-10626) at a dose of either 16.9 mg/kg or 50 mg/kg dose for either 4 days (1720) days post AAV-TBG-Cre treatment) or 14 days (720) days post AAV-TBG-Cre treatment)
doi: 10.3389/fphar.2022.968226 Received 13 June 2022 Accepted 28 July 2022 Published 02 September 2022 Volume 13 - 2022 Edited by Dan-Qian Chen, Northwest University, China Reviewed by Milad Ashrafizadeh, Sabanc University, Turkey Yaser Hosny Ali Elewa, Zagazig University, Egypt Maria Russo, Institute of Food Sciences (CNR), Italy Updates Copyright 2022 Chen, Chen, Tang, Li, Liu, Lu and Gu
Oral dosing relies on the peptide surviving stomach acid and GI enzymes, which reduces bioavailable fraction
How Long Does GHK-Cu Take to Show Results
Local ice application typically lasts 15-20 minutes per session, limited to prevent tissue damage from prolonged cold exposure
