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CAT is one of the most efficient enzymes, since it exhibits one of the fastest turnover rates with a capacity to convert millions of H 2 O 2 molecules per second (kcat = 4 10 7 s 1 ) [45, 48]
Philp, D., et al
Pro-inflammatory cytokines i.e., TNF- and IL-1 may activate the serotoninergic transporter (SERT) via the stimulation of the p38 MAPK pathway, increasing the concentration of other catecholamines in specific brain regions such as the anterior hypothalamus (Zhu et al
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