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Prospective study of hyperhomocysteinemia as an adverse cardiovascular risk factor in end-stage renal disease

The most extensively studied of these is the 677CT polymorphism in the methylenetetrahydrofolate reductase ( MTHFR ) gene, first identified in 1995 as a risk factor for vascular disease and later linked to NTDs

Tang, Z

Malabsorption (insufficient absorption of vitamin B 12 in the intestine), insufficient production of intrinsic factor (a protein that is formed in the gastric mucosa and required to absorb vitamin B 12 ), Diseases in the end section of the ileum (part of the small intestine), e.g

Similarly, analysis of phosphorylated Histone H3 (a marker of cellular division) shows increased expression in 4-day treated animals that is not observed in control animals (Fig