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Studies show the consuming an excessive amount of vitamin B12 may: Increase the risk of cardiovascular events in people with diabetic nephropathy : A study published in JAMA sought to determine whether B vitamin therapy was able to slow the progression of diabetic nephropathy (kidney damage due to diabetes) and prevent vascular complications
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Long-term, high-dose proton pump inhibitors may also affect B12 absorption in some patients
Typical injectable GHK-Cu dose ranges Standard starting dose: 1 mg per day subcutaneous Conservative / beginner dose: 0.5 mg per day Intensive / wound-healing dose: 23 mg per day Upper research range: 4 mg per day (rarely exceeded) Frequency: once daily, or split into morning + evening microdoses for steadier levels Route: subcutaneous (SC) injection - typically abdomen , thigh or flank
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