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It promotes gluconeogenesis in the liver, increases insulin resistance in peripheral tissues, and facilitates lipolysis while paradoxically promoting central adiposity when chronically elevated

Recent studies have reported that elevated levels of Streptococcus, Veillonella, and Enterobacteriaceae involved in BAs metabolism are closely associated with cholestatic liver injury [10]

10.1001/jamainternmed.2017.1419 8 AzenaborA.EkunA

Their NPI numbers are publicly verifiable through the federal NPI registry

In support of this assumption, the N66A mutant does not migrate at the same size as cystinosin(7)-GFP (Supplemental Figure 2, A and B), even though the mutation slightly reduces the protein size (approximately 90 kDa)