[DOI] [PMC free article] [PubMed] [Google Scholar] 329.Naitou K., Mamerto T.P., Pustovit R.V., Callaghan B., Rivera L.R., Chan A.J., Ringuet M.T., Pietra C., Furness J.B
Complicating the matter, administration of ghrelin still leads to cross-desensitization of dopamine-induced Ca 2+ mobilization, and while ghrelin antagonism also reduces this mobilization, it is possible that concurrent cross-sensitization may also occur, which may possibly carry beyond the timeframe of bioavailability of such an antagonist
Following the study period, the femurs of the murine models were analyzed using mid-diaphyseal peripheral quantitative computed tomography (pQCT) scans
Clinical trials have used doses up to 8,000 mg/day for extended periods
The lower end of the dose range is cited for body-size and baseline GH-response reasons