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Some patients need 4-6 weeks before they can tolerate any concentrated sugar without significant side effects, while others adjust within 2 weeks

Current therapies under investigation (Table 8) are targeting muscle-specific kinase (MuSK), which promotes post-synaptic clustering, synaptogenesis via F-actin branching and dendritic proliferation [293], and reduction of aberrant sphingolipid regulation to promote NMJ stability [294]

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Emerging research now suggests a third explanation that clinicians rarely discuss: some patients may have receptor-level biology that limits their response to this entire drug class

A full set of tissues were collected from all animals, processed to slide, stained with hematoxylin and eosin (H&E), and evaluated by Altasciences board-certified veterinary pathologist