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Puerarin, one of the most abundant phytoestrogens with antioxidant activity, could improve myocyte loss during heart failure induced by pressure overload through ferroptosis suppression in rat model [21]

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In this study, we investigated the gene expression of the peroxisomal enzymes carnitine O-octanoyltransferase (CROT) and acyl-CoA oxidase 1 (ACOX1) which both contribute to peroxisomal -oxidation