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however, they should be reserved for inadequate weight loss despite implementing lifestyle interventions, according to the American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE) 2016 clinical practice guideline

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Manufacturer IP Strategy Under PBM Pressure: Evergreening, Lifecycle Management, and Formulary Defense The Evergreening Toolkit and Its Formulary Interaction Pharmaceutical manufacturers pursue lifecycle management strategies commonly called evergreening to extend the effective commercial exclusivity of branded drugs beyond the expiration of the primary compound patent

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