India is home to over 100 million people with diabetes and approximately 250 million classified as obese or overweight.[15] What makes the situation uniquely dangerous is the Thin-Fat Indian paradox: South Asians tend to accumulate more visceral (belly) fat, liver fat, and less lean muscle mass at lower body weights than Western populations.[8][9][10] While GLP-1 medications are a global phenomenon, they are particularly critical for the Thin-Fat Indian phenotype
This is supported by cell-killing assays which indicate increased lysis of NK cell-sensitive lines after GLP-1 treatment, alongside heightened production of IFN- and granzyme B [173]
Eur Heart J 27(19):23382345 Levitan EB, Wolk A, Mittleman MA (2009) Relation of consistency with the dietary approaches to stop hypertension diet and incidence of heart failure in men aged 45 to 79 years
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Hong SY, Gil HW, Yang JO, Lee EY, Kim HK, et al
