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Gastrointestinal side effects like nausea, vomiting, or diarrhea are common but often improve with proper titration

The production of PUFAs requires the activation of the ACSL4-LPCAT3 (acyl-CoA synthetase long-chain family member 4-lysophosphatidylcholine acyltransferase 3) pathway

However, various factors such as aging, stress, and environmental pollutants can deplete its levels, necessitating external supplementation

It urges regulatory agencies such as the FDA and EMA to monitor these drugs closely and calls on clinicians to balance their benefits with caution

In the brain, it blocks the reward response, she said