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The absence of disulfide bonds simplifies quality control compared to cysteine-containing peptides

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In McCormick DB, Wright LD (eds.)

As a result, our finding that small urinary peptides increased in abundance in IC/BPS urine is likely a result of increased proteolysis occurring in the urine or the bladder wall, which is consistent with the inflammatory and immune responses (e.g., mast cell activation) associated with this disorder 1,2,3,4,5,11

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