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In vivo and in vitro evidence confirms that acute alcohol intake can stimulate autophagy in hepatocytes, which may be directly related to the activation of the CYP2E1 pathway and the generation of ROS (Salete-Granado et al., 2023)

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[4] Pharmacokinetics and Distribution Pharmacokinetic work in mice reported systemic exposure and distribution of 5-Amino-1MQ to metabolically active tissues, including adipose, muscle, and liver, after subcutaneous compound application