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Given the metabolic and inflammatory components of lipedema, medications that address these pathways have generated clinical interest, including newer incretin-based therapies originally developed for type 2 diabetes and obesity management

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As discontinuation and reinitiation rates varied significantly depending on the length of the grace period used to define treatment discontinuation, and as many patients reinitiated treatment after discontinuation, we performed a post hoc analysis to assess the proportion of patients covered by treatment [31]

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