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Autonomic nervous system function predicts the inflammatory response over three years in newly diagnosed ulcerative colitis patients

The New Jersey-based biotechs candidate is made up of oxytocin and formulated with magnesium to enhance oxytocin receptor binding and signaling

Adding GIP signaling appears to enhance insulin response and metabolic efficiency, delivering even greater weight reduction and glycemic control

Food Res Int 140:110064

Side Effects: Sedation Parkinsonism symptoms QT prolongation (may be significant if taking with drugs inhibiting CYP3A4/5 or 2D6) Pharmacokinetics: undergoes rapid hepatic metabolism involving carbonyl reductase and CYP2D6 to 2 deuterated active metabolites -dihydrotetrabenazine (-HTBZ) and -dihydrotetrabenazine (-HTBZ), with eventual renal elimination of metabolites the -HTBZ and -HTBZ metabolites are primarily responsible for the pharmacological & therapeutic effects produced by the parent prodrug twice a day dosing effect half life 9.4 hours (Schneider et al, 2021) HT: Resistant Hypertension