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Semaglutide was first approved as a onceweekly injection at maintenance doses of 0.5 and 1 mg by the FDA in 2017 6 and by the European Medicines Agency (EMA) in 2018

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The new GLP-1 ID protocol was developed in response to outcomes observed in a retrospective study published in Obesity Pillars (June 2025), which analyzed 1,131 patients treated through Ivm's virtual GLP-1 program