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This does not invalidate the findings but adds a potential source of bias Single-blind only: While the investigator assessing photos was blinded, patients knew whether they received the active serum or saline, which could influence self-reported satisfaction scores No long-term follow-up: The study ended at 6 months

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Die zyklische Anwendung ist primr zur Erhaltung der Rezeptor-Sensitivitt, nicht zur Entzugsvermeidung

However, its always best to start with a smaller dose and see how your body reacts before increasing

The birefringence of porphyrin appears to be associated with bilamellar components within the pigment (Stejskal et al